Document from the year 2018 in the subject Nursing Science, grade: 1, Egerton University, language: English, abstract: The purpose of this paper is to discuss the significance of evidence based practice in improving patient outcomes. It is aimed at discussing the significance of adopting evidence based practice based on the PICOT question. In this case, the PICOT question states, “In patients diagnosed with HPV, what is the effect of human papillomavirus vaccination compared to no treatment on HPV rates?” This question has immense significance to nursing practice because it offers an opportunity for understanding how the adoption of this evidence based practice leads to better outcomes. Human papillomavirus vaccination exhibits effectiveness in reducing the rates of infection.